Chosen Solution
After replacing the screen on my iPhone 5s (16GB white and silver) the left side has some daed spots, I cannot press ‘Q’ or ‘1’ in portrait, the bottom left icon also doesn’t work. What should I trouble shoot? There are no strange lines or screen bleeds.
I would open it back up again and reconnect the digitizer cable, maybe there is some dirt in the connector? Give it a wipe with isopropyl if you have any. If that doesn’t work, it might suggest that the new screen is faulty. Also check the phone is not bent, did you have a hard time getting the screen to clip back into the frame? I once did a screen repair on a 5S, that had similar problems you describe, on close inspection, I noticed the iPhone was bent, and so the new screen was obviously bending to the shape of the frame.
Make sure you screen is not being pressured by anything. Try loosing the LCD Shield plate scews and check the phones reaction. As Michael stated, if the iPhone is bent, the new screen will follow the shape of the frame and it would damage the new screen. If there’s no line on your screen and everything is shining bright, the cables are probably not the cause of your issue. Regards, Bruno